Dopamine D2 receptor overexpression in cholinergic interneurons of the nucleus accumbens may explain why some are more prone to cocaine addiction than others.
Dietary triglycerides directly alter signaling in the reward circuit to regulate behavior. The findings reveal a potential mechanism by which triglyceride-rich diets may lead to adaptions in dopamine signaling that underlie reward deficit and compulsive behaviors.
18 genetic variants have been identified which appear to be associated with alcohol use disorder and heavy drinking. Of these genes, five were overlapped, eight were associated with heavy consumption and five were linked to an increased risk of AUD. The study concluded that while heavy drinking is a risk factor for alcoholism, it is not a sufficient cause of the disorder.
People with a variation of the DRD2 gene are more resilient to the effects of sleep deprivation when completing tasks that require cognitive flexibility, a new study reports.
Study finds a sex difference in a gene linked to substance abuse risk in adolescents.
The effect music has on people may be genetically determined by dopamine functionality, a new study reports.
A new study identifies a microRNA that may be essential to restoring normal function in a brain circuit associated with auditory hallucinations in schizophrenia.
Researchers have identified two groups of serotonin neurons that may help to suppress aggression in mice.
Researchers report on a link between the dopamine system and initiating joint attention in children at high risk for autism.
Researchers report a disruption in a brain circuit could contribute to the auditory hallucinations associated with schizophrenia.