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Down syndrome

Image shows neurons in the cerebral cortex.

·April 5, 2016·5 min read

Gene Linked to Down Syndrome Associated With Altered Oscillations in Cerebral Cortex

Researchers have identified alterations in neural circuitry that impact cerebral cortex pathology. These alterations could be key to cognitive deficits in Down syndrome.

Featured Genetics Neurology Psychology

·June 26, 2018·5 min read

Genes Linking Alzheimer’s to Down Syndrome Discovered

Researchers report extra copies of genes on chromosome 21 increase Alzheimer's like pathology and cognitive impairment in mouse models of Down syndrome. The findings provide insight into early onset Alzheimer's in those with Down syndrome.

This is a generic image of neurons and synapses.

Featured Neuroscience

·August 3, 2015·3 min read

Hippocampal Circuit Abnormalities Linked to Learning Difficulties in Down Syndrome

A new study sheds light into a possible cause of learning difficulties in Down syndrome.

This shows neurons in the developing neocortex.

Featured Neurology Neuroscience

·April 23, 2026·13 min read

How Down Syndrome Reshapes the Developing Brain

A new study provides a cellular-resolution map of Down syndrome brain development, identifying a depletion of progenitor cells as the cause of smaller brain size.

Featured Genetics Neurology

·October 11, 2018·4 min read

Human Brain Cell Transplant Offers Insight into Neurological Conditions

Researchers have successfully transplanted human brain cells into mouse brains and watched how they grow to form networks. The technique could be used to study a range of neurological conditions, the researchers report.

Featured Neuroscience

·August 16, 2022·5 min read

Issues With Fracture Healing in People With Down Syndrome

Researchers report bone fractures in those with Down syndrome are unlikely to fully heal.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 21, 2020·3 min read

Major discovery in the genetics of Down syndrome

Study explains how an overexpression of the RCAN1 gene may cause intellectual disabilities in people with Down syndrome.

This image is a photo of a plastinated Alzheimer's brain.

Featured Genetics Neurology Open Neuroscience Articles

·July 21, 2015·4 min read

New Culprit in Alzheimer’s Disease Development Identified

Researchers have implicated a new culprit in the development of Alzheimer's disease. The findings could influence new strategies for treatment.

Image shows amyloid beta attacking a cell.

Featured Genetics Neurology Open Neuroscience Articles

·September 17, 2015·4 min read

Pathogenic Role of Amyloid Beta in Alzheimer’s Disease and Down Syndrome Dementia Confirmed

A new study furthers insight into how Alzheimer's disease naturally progresses.

Featured Genetics

·February 25, 2016·3 min read

Pinpointing a Potential Treatment Target for Down Syndrome

A new study of gene activity in the brains of people with Down syndrome reveals the formation of white matter is affected throughout life.

Featured Neuroscience

·May 17, 2017·4 min read

Placebo Effect Despite Intellectual Disability

A new study provides contrary evidence to popular belief and states people with congenital intellectual disabilities are sensitive to placebo-like effects.

This shows the outline of two heads made up of tree branches

Featured Neurology Neuroscience

·March 29, 2022·4 min read

Promising Alzheimer’s Drug May Also Improve Memory in Down Syndrome and Normal Aging

GM-CSF/sargramostim, a drug that improved memory in Alzheimer's patients during a phase II clinical trial, also appears to improve cognitive function in older adults and those with Down syndrome.