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dopaminergic neurons

Featured Genetics Neurology Neuroscience

·October 3, 2018·3 min read

Fly Protein Has Protective Effect on Dopaminergic Neurons

Researchers report the Scarlet protein has a neuroprotective effect on dopaminergic neurons in fruit flies.

Featured Neuroscience

·October 26, 2012·2 min read

Stimulating Brain Cells with Light

The work will be conducted on laboratory rats modelling Parkinson’s disease. The transplanted cells will be derived from skin from an adult human and will have been “reprogrammed” as nerve cells. The light-sensitive protein is obtained from a bacterium, which uses light to gain energy.

The image shows the structure of protein LRRK2.

Featured Genetics

·February 6, 2013·4 min read

Study Points to Possible Cause and Treatment for Non-familial Parkinson’s

Researchers identify a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson’s disease. The study implicates two genetic variants that disrupt protein sorting in neurons.

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons.

Image shows dopamine neuron clusters in a fruit fly brain.

Electrophysiology Featured Neuroscience

·October 8, 2015·4 min read

New Role for Calcium Refill Mechanism in Regulating Dopamine

A process which helps maintain calcium levels in cells may also play a role in maintaining dopamine levels, researchers report.

this is a woman holding her head while other hands are covering her face

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·May 3, 2019·5 min read

Hotspot in the genome may drive psychosis in schizophrenia and bipolar disorder

A cluster of epigenetic marks in an enhancer at IGF2 could enhance dopamine synthesis associated with psychosis in schizophrenia and bipolar disorder. The findings may help in devising more effective treatments and screening strategies for both disorders.

An image of stem cells is shown. Caption describes well.

Featured Neurology

·October 19, 2012·4 min read

Scientists Pinpoint Key Player in Parkinson’s Disease Neuron Loss

Stem cell study may help to unravel how a genetic mutation leads to Parkinson's symptoms. By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers identified damage to neural stem cells as a powerful player in Parkinson's disease.

The image shows three double helix strands.

Featured Neurology Open Neuroscience Articles Psychology

·April 7, 2015·6 min read

Scientists Find Molecular Trigger of Schizophrenia-Like Behaviors and Brain Changes

Scientists at The Scripps Research Institute (TSRI) have identified a molecule in the brain that triggers schizophrenia-like behaviors, brain changes and global gene expression in an animal model.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 6, 2019·3 min read

Nicotine Exposure During Pregnancy Alters Dopamine Neurons and Genes in Newborns

A new study reports chronic nicotine exposure during pregnancy alters the genetics and dopamine neurons of newborns. The findings could help researchers develop a possible cure for nicotine addiction.

Featured Genetics Neurology Neuroscience

·September 22, 2022·3 min read

Aged Neurons Generated Directly From Skin More Accurately Model Parkinson’s Disease

Researchers successfully turned skin cells from Parkinson's patients into dopaminergic neurons by introducing a combination of neural-inducing genes into the skin cells.

The gut and brain are highlighted in this drawing of a man

Featured Genetics Neurology Neuroscience

·July 17, 2019·5 min read

Bacterial intestinal infections may trigger Parkinson’s disease

Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.

Featured Neurology

·February 10, 2016·3 min read

Teaching Neurons to Respond to Placebos Could Help Treat Parkinson’s

Researchers have discovered a way to make neurons respond to placebos. They believe the findings could be used as a potential treatment for Parkinson's disease.

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dopaminergic neurons

Fly Protein Has Protective Effect on Dopaminergic Neurons

Stimulating Brain Cells with Light

Study Points to Possible Cause and Treatment for Non-familial Parkinson’s

More evidence Parkinson’s disease may start in the gut

New Role for Calcium Refill Mechanism in Regulating Dopamine

Hotspot in the genome may drive psychosis in schizophrenia and bipolar disorder

Scientists Pinpoint Key Player in Parkinson’s Disease Neuron Loss

Scientists Find Molecular Trigger of Schizophrenia-Like Behaviors and Brain Changes

Nicotine Exposure During Pregnancy Alters Dopamine Neurons and Genes in Newborns

Aged Neurons Generated Directly From Skin More Accurately Model Parkinson’s Disease

Bacterial intestinal infections may trigger Parkinson’s disease

Teaching Neurons to Respond to Placebos Could Help Treat Parkinson’s

Protein Key to Lifespan and Healthy Aging Identified

Unlocking Genes Behind Neurodevelopmental Disorders

Placebo Power: Patient Belief in Treatment Impacts Depression Therapy Effectiveness

Redefining Myelin Damage

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