Long-term aim is to develop new treatments to block the spread of damaged proteins in the brain. Van Andel Institute...
Dopamine receptors have different molecular features and functions depending on their anatomical location within the striatum. The findings could help develop better-targeted treatments for a range of disorders from schizophrenia to Parkinson's disease.
Researchers report arginine methylation regulates dopamine signaling in human cells.
Researchers report on a link between the dopamine system and initiating joint attention in children at high risk for autism.
Researchers link physical inactivity in obese mice to altered dopamine receptors rather than their body weight.
Researchers have discovered a connection between a lack of ovarian hormones and changes in the nucleus accembens following menopause.
Researchers report a blockade of D2 receptors in interneurons can increase acetylcholine signaling above threshold on neighboring neurons, resulting in motor abnormalities.
Study reveals how the mechanism for storing olfactory memories differs slightly from erasing unnecessary memories. Understanding how the brain gets rid of unimportant memories could help unlock new avenues of research to better understand memory loss in aging, researchers say.
A new study reveals a lack of dopamine transmission via D1 receptors disrupts information flow in the basal ganglia and can cause difficulty in initiating voluntary movements for Parkinson's patients.
New evidence that receptors for brain’s ‘reward’ chemical provide protection. Brain scans of two strains of mice imbibing significant quantities...
According to a new study, alcohol consumption alters the function of medium spiny neurons in the dorsomedial striatum.