Combining Disulfiram, a medication commonly used to treat chronic alcoholism, with copper ions kills medulloblastoma cancer cells and prevents new ones from growing.
Disulfiram, a drug commonly prescribed to treat chronic alcohol addiction, was shown to reduce anxiety levels in rodent models. The drug inhibits FROUNT protein and chemokine signaling pathways under its influence, suppressing overall glutamate transmission in the brain. This, in turn, helps reduce overall activity. The findings may signal a new way to treat anxiety in humans.