Higher levels of plasmin, an enzyme involved in blood clotting prevention, enhances the virulence and infectivity of SARS-CoV-2 by cleaving its spike proteins. Enhanced levels of plasmin are common in a range of diseases, including diabetes and heart disease. The findings shed light on why those with hypertension and diabetes are at increased risk of complications following coronavirus infection.
Previous studies of related coronaviruses SARS and MERS found blocking DPP4 activity reduced inflammatory response. Researchers suggest drugs that target DPP4 could help to reduce the overexpression of inflammatory cytokines seen in severe COVID-19.
Based on data from COVID-19 patients from Wuhan, China, that died as a result of the infection, researchers have identified many symptom commonalities the patients shared.
Consumed alone, artificial sweeteners do not appear to have a negative impact. However, when consumed with carbohydrates, insulin sensitivity changes and the brain has a decreased response to sweet tastes.
In the short term, a ketogenic diet can help improve health as well as assist in weight loss. However, the negative effects of the keto diet start to appear after one week. Mice who were fed a ketogenic-style diet for more than seven days consumed more fat than they could burn, and had an increased risk of developing diabetes and obesity.
Daily time-restricted feeding and limiting yourself to one moderate-sized meal two days a week may have significant benefits for both cognitive and overall health. A new study links intermittent fasting to a longer, healthier life.
From reducing memory capability to increasing the risk of diabetes and obesity, researchers investigate how sugar affects the brain and body.
A new study shows how the microbiome communicates with cells producing serotonin to influence blood sugar levels. The microbiome can worsen metabolism by signaling to cells in the gut that produce serotonin. This drives up serotonin levels. The rise in blood serotonin levels causes metabolic problems.
Women who suffer from a chronic physical condition, such as asthma or diabetes, are at increased risk of developing mental health problems both during pregnancy and up to one-year postpartum.
Ginkgo Biloba, a popular herbal supplement, may help in the treatment of Type 2 diabetes. The supplement had a promising effect on beta cells of Langerhans in rat models of the disease. Additionally, Ginkgo Biloba reduced oxidative stress associated with type 2 diabetes.
Whole-body vibration (WBV) therapy may be a way in which inflammation associated with diabetes can be controlled. WBV alters the microbiome, increasing levels of a bacterium that creates short-chain fatty acids, which help the body to better use glucose.