Latest

depression

Featured Genetics Neuroscience Psychology

·July 21, 2025·7 min read

Most Mental Illnesses Arise Without Family History

A massive Danish study shows that most mental illnesses—like schizophrenia, bipolar disorder, and depression—occur in people with no close family history of the condition. Analyzing data from over 3 million individuals, researchers found that while heredity increases risk, most diagnosed individuals do not have affected relatives.

This shows a pregnant woman and gut bacteria.

Featured Neuroscience Psychology

·July 21, 2025·7 min read

Pregnancy Stress Disrupts Baby’s Microbiome, Increasing Depression Risk

Prenatal stress in mothers can leave a lasting imprint on their offspring, predisposing them to depression-like behaviors. Researchers found that maternal stress disrupts the gut microbiome and metabolite production, which are vertically transmitted to the young.

Featured Genetics Neuroscience Psychology

·July 19, 2025·6 min read

Genetic Link Between Cannabis Use Disorder and Mental Health

A large genetic study reveals that cannabis use disorder (CanUD) is strongly linked to increased risk for multiple psychiatric disorders, including depression, PTSD, ADHD, and schizophrenia. By analyzing global and local genetic correlations, colocalization, Mendelian randomization, and structural equation modeling, researchers showed CanUD has distinct genetic signatures compared to casual cannabis use.

Featured Neuroscience Psychology

·July 19, 2025·6 min read

More Than Serotonin: How Psychedelics Engage the Whole Brain

Classical psychedelics like LSD, psilocybin, and mescaline are known for activating the 5-HT2A serotonin receptor, but a new study reveals their effects go far beyond. Researchers profiled 41 psychedelics against over 300 human receptors and found potent activity at serotonin, dopamine, and adrenergic sites.

Featured Genetics Neuroscience Psychology

·July 19, 2025·7 min read

Why Antidepressants Work Better for Some

A meta-analysis of gene expression data from humans and rodents reveals key biological pathways influencing response to the antidepressant fluoxetine. The study highlights the role of immune-related pathways, including toll-like receptor signaling, and neural signal transduction mechanisms in distinguishing responders from non-responders.

Featured Neuroscience Psychology

·July 17, 2025·8 min read

Overactive Anterior Insula May Fuel Anxiety and Depression

New research shows that elevated glutamate-glutamine (Glx) levels in the anterior insular cortex (AIC) make people more sensitive to mistakes and more prone to anxiety and depression. Using functional magnetic resonance spectroscopy and reinforcement learning tasks, scientists found that high AIC Glx predicted both a general internalizing symptom score and heightened error sensitivity, which mediated this relationship.

This shows supplement bottles on a shelf.

Featured Neuroscience Psychology

·July 16, 2025·7 min read

Do Supplements Work for Depression? Some Do, Study Says

A comprehensive review of over 23,000 studies identified 64 over-the-counter (OTC) supplements and herbal products evaluated in clinical trials for depression. St John’s Wort, saffron, probiotics, vitamin D, and omega-3s showed the strongest evidence, while others like lavender, zinc, and chamomile showed promise but need more research.

Featured Neuroscience Psychology

·July 7, 2025·5 min read

Timing of Prozac Treatment Shapes Lasting Mood, Brain Changes

New research reveals that the developmental timing of fluoxetine (Prozac) treatment profoundly influences long-term mood and brain function. In a rodent model, early postnatal treatment in males led to persistent anxiety and depression-like behaviors, while adolescent treatment reduced these behaviors.

Featured Neuroscience Psychology

·June 28, 2025·5 min read

Exercise Proven to Boost Kids’ Mental Health

A massive analysis of over 375 trials shows that structured exercise significantly reduces depression and anxiety in children and teens. Low-intensity resistance activities like light weights were most effective for easing anxiety, while moderate mixed-mode programs worked best for depression—especially when lasting under 12 weeks.

Featured Neuroscience Psychology

·June 28, 2025·4 min read

Lingering Brain Changes May Raise Depression Relapse Risk

Even after symptoms subside, people who’ve experienced depression may retain a heightened sensitivity to punishment and negative feedback. A new study found that the brain's habenula—key to processing aversive signals—remains hyperactive in those with remitted depression, particularly during the anticipation of unpleasant outcomes.

Featured Neuroscience Psychology

·June 25, 2025·4 min read

Autoimmune Disease Doubles Risk of Depression and Anxiety

People living with autoimmune diseases face nearly twice the risk of developing persistent mental health disorders like depression, anxiety, and bipolar disorder, according to a massive UK-based study. Researchers suggest chronic inflammation may play a key role in this connection, especially in women who showed significantly higher risk levels than men.

Featured Neuroscience Psychology

·June 20, 2025·6 min read

Ketamine Plus Therapy Offers Lasting Relief for Severe Depression

A first-of-its-kind clinical trial shows that ketamine treatment for severe, treatment-resistant depression is significantly more effective when paired with psychotherapy and supportive environments. Patients who underwent this combined treatment reported a 30% drop in depression symptoms, with reduced anxiety and suicidal thoughts lasting at least eight weeks.

1 2 3 4 … 146

depression

Most Mental Illnesses Arise Without Family History

Pregnancy Stress Disrupts Baby’s Microbiome, Increasing Depression Risk

Genetic Link Between Cannabis Use Disorder and Mental Health

More Than Serotonin: How Psychedelics Engage the Whole Brain

Why Antidepressants Work Better for Some

Overactive Anterior Insula May Fuel Anxiety and Depression

Do Supplements Work for Depression? Some Do, Study Says

Timing of Prozac Treatment Shapes Lasting Mood, Brain Changes

Exercise Proven to Boost Kids’ Mental Health

Lingering Brain Changes May Raise Depression Relapse Risk

Autoimmune Disease Doubles Risk of Depression and Anxiety

Ketamine Plus Therapy Offers Lasting Relief for Severe Depression

AI Robots Learn Touch and Vision to Handle Objects Like Humans

How the Brain Extinguishes Fear Memories

Cheerful Music Could Be the Cure for Carsickness

New Brain Map Shows How Decisions Emerge Across the Brain

Subscribe