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          depression

          This shows a depressed person.
          FeaturedNeurosciencePsychology
          ·June 20, 2025·6 min read

          Ketamine Plus Therapy Offers Lasting Relief for Severe Depression

          A first-of-its-kind clinical trial shows that ketamine treatment for severe, treatment-resistant depression is significantly more effective when paired with psychotherapy and supportive environments. Patients who underwent this combined treatment reported a 30% drop in depression symptoms, with reduced anxiety and suicidal thoughts lasting at least eight weeks.
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          This shows a woman's head.
          FeaturedNeurosciencePsychology
          ·June 19, 2025·5 min read

          Multiple Brain Profiles May Underlie the Same Depressive Symptoms

          A new study reveals that the same clinical signs of depression may stem from different brain profiles, highlighting both one-to-one and many-to-one brain-symptom mappings. Using brain imaging data from the UK Biobank, researchers found that even when patients experience similar symptoms, their underlying neurobiology may differ significantly.
          Read More
          This shows sad teens.
          FeaturedNeurosciencePsychology
          ·June 19, 2025·4 min read

          Childhood Emotion Struggles Linked to Teen Anxiety and Depression

          Children who have trouble managing their emotions at age seven are more likely to experience anxiety and depression during their teenage years, a new study finds. Researchers analyzed data from the UK Millennium Cohort Study, tracking emotional development and mental health from childhood to age 17.
          Read More
          This shows a dad and a baby.
          FeaturedNeurosciencePsychology
          ·June 16, 2025·4 min read

          Neglecting Dads’ Mental Health May Harm Kids’ Development

          Experts urge healthcare providers to screen new fathers for mental distress, citing strong evidence that paternal mental health affects child development. Depression, anxiety, and stress in new dads are linked to poorer outcomes in children's emotional, cognitive, and social growth.
          Read More
          This shows a patient.
          FeaturedNeurosciencePsychology
          ·June 13, 2025·7 min read

          ECT Cuts Suicide Risk by 34% in Severe Depression

          A new meta-analysis reveals that Electroconvulsive Therapy (ECT) reduces suicide risk by 34% and all-cause mortality by 30% in individuals with severe depression. The study, which pooled data from 26 high-quality studies, compared nearly 18,000 patients treated with ECT to over 25,000 who received standard care. ECT also modestly reduced suicidal thoughts, showing broader health benefits beyond mental health. While newer therapies like rTMS and VNS showed some promise, the evidence was too limited to draw firm conclusions.
          Read More
          This shows a mouth and bacteria.
          FeaturedNeurosciencePsychology
          ·June 12, 2025·5 min read

          Oral Bacteria Diversity Linked to Depression Symptoms

          A new study reveals that lower diversity of microbes in the mouth is associated with greater symptoms of depression. Researchers analyzed data from over 15,000 U.S. adults, comparing their mental health surveys with saliva samples to assess microbial diversity.
          Read More
          This shows the outline of a person.
          FeaturedNeurosciencePsychology
          ·June 12, 2025·4 min read

          Negative Surroundings Skew Emotions in People with Depression

          People with depressive symptoms are more likely to interpret neutral images as negative when those images are surrounded by unrelated negative visuals. This emotional “spillover” effect shows how peripheral cues—like background imagery or context—can shape our emotional responses more than we realize.
          Read More
          This shows twins and DNA.
          FeaturedGeneticsNeurosciencePsychology
          ·June 10, 2025·6 min read

          Genetic Sensitivity to Environment May Shape Mental Health Traits

          A large international study of over 21,000 identical twins has identified genetic variants that influence how individuals respond to life experiences, affecting traits such as anxiety, depression, and autistic traits. By analyzing genetic differences in identical twins, researchers discovered that certain genes make people more or less sensitive to environmental exposures.
          Read More
          This shows an older woman and a brain.
          FeaturedNeurologyNeurosciencePsychology
          ·June 10, 2025·5 min read

          Late-Life Mood Disorders May Foreshadow Alzheimer’s

          Late-life depression and bipolar disorder may be more than psychiatric conditions—they could be early warning signs of neurodegenerative diseases like Alzheimer’s. Using advanced brain imaging and postmortem tissue analysis, researchers found that half of the participants with late-onset mood disorders showed signs of tau accumulation, a key hallmark of neurodegeneration.
          Read More
          This shows a sad man with a plate.
          FeaturedNeurosciencePsychology
          ·June 4, 2025·5 min read

          Low-Calorie Diets May Increase Depression Risk

          New research links low-calorie diets with a slight increase in depressive symptoms, particularly among overweight individuals and men. The large observational study analyzed dietary habits and depression scores in over 28,000 U.S. adults.
          Read More
          This shows a brain.
          FeaturedGeneticsNeurosciencePsychology
          ·June 3, 2025·4 min read

          Shared Genetic Signatures Found Across Psychiatric Disorders

          Researchers have uncovered shared biological mechanisms across major psychiatric disorders by analyzing postmortem brain samples from the dorsolateral prefrontal cortex. Instead of looking at gene expression broadly, they zoomed in on the exon level—the building blocks that influence how proteins are made.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·May 31, 2025·3 min read

          Brain ‘Reset Wave’ May Explain How ECT Rapidly Relieves Depression

          Electroconvulsive therapy (ECT), long misunderstood due to outdated portrayals, remains the most effective treatment for severe, treatment-resistant mental illness. While traditionally thought to work solely through induced seizures, new research reveals that ECT also triggers a second brain event: cortical spreading depolarization (CSD).
          Read More
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          Could Mental Illness Begin Before You’re Born?

          This shows an older man with a cane walking in a colorful hill system, emphasizing he is looking for his life's meaning.

          Discovering Life’s Meaning Through Emotion and Exploration

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          Old Injuries Rewire the Brain to Feel Fear and Pain Forever

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          Microglia May Hold Key to Slowing Alzheimer’s Progression

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