A new computer model shows the beneficial effects of deep brain stimulation arise from how it interrupts the cycle promoting runway beta in a circuit loop between the subthalamic nucleus and striatum.
Combining deep-brain stimulation with intracranial EEG, researchers achieved an individualized understanding of specific brain networks that contributed to an individual's depression symptoms and identified stimulation patterns best suited to each patient for symptom relief.
A new, improved DBS technique that targets specific subpopulations of neurons in the globus pallidus with short bursts of stimulation shows promising results as a treatment for Parkinson's disease.
A modified deep brain stimulation devise that delivers on-demand stimulation when it recognizes changes in brain patterns provides immediate and long-term relief for depression sufferers.
Researchers have successfully recorded brain signatures of movement symptoms and deep brain stimulation of Parkinson's patients in real time. The findings could lay the groundwork for personalize therapies for those with the neurodegenerative disease.
Researchers have succeeded in wirelessly recording both deep and surface human brain activity for an extended period of time while the patient was in their home environment.
Spinal cord stimulation significantly decreased pain and reduced motor symptoms associated with Parkinson's disease, both as a singular therapy and for those who deep brain stimulation proved ineffective.
Researchers use optogenetic based deep brain stimulation to help treat motor dysfunction in animal models of Parkinson's disease. The new technique provides insights into why DBS works and ways in which it can be improved on a patient-by-patient basis.
Stimulating the central lateral thalamus in monkeys under anesthesia was enough to wake the animals and elicit normal waking behaviors.