Researchers have identified four genes, ESR1, DCC, DRD2, and TRAF3, that are associated with an increased risk of suicidal thoughts and actions.
A new genetically based scoring model can accurately detect children most at risk of developing impulsive behaviors.
The largest genetic map of mental health disorders to date reveals there are three groups of highly genetically related disorders among eight psychiatric disorders. A gene related to nervous system development is a risk factor for all eight disorders studied. The RBFOX1 gene is implicated in seven of the eight disorders. ADHD and depression share 44% of genetic risk factors common in the general population. 109 pleiotropic loci affect more than one disorder. These pleiotropic loci are within genes that show heightened expression in the brain through the lifespan, beginning during the second trimester of pregnancy.
Researchers have identified a new syndrome caused by mutations in the DCC gene which can lead to a range of disabilities.
Researchers delve into the details of molecular interactions which help guide neurons towards their anatomical boundaries.
Researchers isolate a gene responsible for dopamine connectivity in the medial prefrontal cortex during adolescence.
A new study reveals DCC, the receptor for a crucial protein in the nervous system known as netrin, plays a key role in regulating the plasticity of nerve cell connections in the brain.