Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.
Mouse study identifies specific neurons and a signaling pathway to regions of the hindbrain that mediate sexual reproductive activity and physical activity that appear to influence activity behaviors during ovulation. The findings may provide valuable insights into how estrogen loss during menopause disrupts this activity.
Researchers have encoded a 'primitive' video from the DNA in living cells. The Nature study reports this is the first step towards a 'molecular recorder' that could make it possible to get read-outs of changing internal states of neurons as they develop in the brain.
The ability to select specific traits, such as height or IQ, brought about by multiple genes is more complicated than most people realize.
Researchers have developed a new method to accurately and rapidly locate proteins within brain cells.
Rockefeller University researchers reveal Huntington's neurons are much larger than healthy cells.
Using CRISPR gene editing, researchers introduce the SHANK3 gene variant into macaque monkeys. SHANK3 has previously been linked to autism in humans. The monkeys with the SHANK3 mutations exhibited behavioral traits and brain activity patterns similar to those seen in humans on the autism spectrum, Researchers hope the new model will facilitate new avenues of research for ASD.