The ion channel TRPC5 acts as a molecular cold sensor in teeth. Researchers report the TRPC5 could be a new target to help treat pain from toothaches and cold sensitivity.
By stimulating cold and nicotine receptors, researchers successfully improved metabolism in mice, helping them to lose weight. Further studies will investigate whether the same results can be achieved in humans.
A new study using fruit fly models could help researchers better understand the genetic and neural bases of detecting cold or painful stimuli.
