Physical activity appears to reduce microglial activation and improve cognition in the aging human brain, researchers report.
A new framework reveals Alzheimer's disease is far more complex than previously believed. Rather than being a disease where the same causes produce the same outcomes, researchers found three different models for the disease, each with its own characterizations and dynamics.
Older adults who sleep less than 4.5 hours, or more than 6.5 hours per night and who experience sleep disruptions are at greater risk of cognitive decline, researchers report.
In both aging human and mouse experiments, researchers identified a link between the MEF2 gene and cognitive resilience. Findings suggest enhancing MEF2 activity could protect the brain against age-related dementia.
While the positive impact of breastfeeding on babies is well known, little is known about the positive benefits for the mother. A new study reveals women who breastfed their children performed better on cognitive tests at age 50 than those who fed their children with an alternative method.
A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus.
People with genetic risks for Alzheimer's disease may exhibit changes in brain structure and reduced performance in cognitive tests long before symptoms of the neurodegenerative disease become obvious.
PET study finds early accumulation of the tau protein in the brain is a better predictor of Alzheimer's associated memory decline than amyloid plaque accumulation or cerebrospinal fluid biomarkers.
Higher glucose levels detected by a two-hour glucose test were an accurate predictor of poorer performance in tests of episodic memory ten years later.
Researchers have identified four cognitive profiles associated with menopause. Findings reveal women who experience stronger verbal learning and memory, in addition to better attention and executive function during menopause, are less likely to experience hot flashes and depression. Women who experienced cognitive weakness had an increased risk of depression and sleep disruptions.