Researchers at Yale School of Medicine have zeroed in on a set of neurons in the part of the brain...
Results of a new study offer compelling evidence for the first time that mephedrone, like cocaine, does have potential for abuse and addiction. “The effects of mephedrone on the brain’s reward circuits are comparable to similar doses of cocaine,” Dr. Malanga, a professor of neurology, pediatrics and psychology at UNC School of Medicine said. “As expected our research shows that mephedrone likely has significant abuse liability.”
Scientists used an electronic prosthetic system to tap into existing circuitry in the brain at the cellular level and record the firing patterns of multiple neurons in the prefrontal cortex, the part of the brain involved in decision-making. They then “played” that recording back to the same brain area to electrically stimulate decision-based neural activity. Not only did it restore function, in some cases, it also improved it.
Topiramate, a drug used to treat migraine headaches and epilepsy, could also help treat cocaine addiction, a new study reports.
A new study reports repetitive transcranial magnetic stimulation appears to reduce cocaine use and cravings in those addicted to the drug.
A new study examines the link between substance abuse and suicide risk.
A new study reports microglia can diminish the adverse changes to neural circuitry bought on by chronic cocaine use.