Using optogenetics to stimulate the amygdala, researchers intensify the desire to consume cocaine in rats.
Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.
Gene therapy shows promise for future treatment of addiction in humans, a new study reports.
Cannabis use during youth enhances sensitivity to cocaine from the first exposure, a new rat study finds.
Disrupting memories associated with environmental cues significantly reduces cocaine seeking behaviors in rat models of addiction, a new study reports.