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cocaine addiction

Featured Neuroscience Open Neuroscience Articles Psychology

·January 10, 2017·5 min read

Revealing The Connection Between Female Estrogen Cycle and Cocaine Addiction

According to a new study, cocaine has the most potent effects on the female brain when estrogen levels are at their highest.

The image shows the location of the nucleus accumbens in the brain.

Featured Neuroscience Psychology

·June 27, 2014·4 min read

Bad Learning

Researchers discover a new form of neurotransmission which influences the long term memory created by addictive drugs.

Featured Neuroscience Psychology

·October 8, 2022·4 min read

Human Cocaine and Heroin Addiction Is Found Tied to Impairments in Specific Brain Circuit Initially Implicated in Animals

Greater impairment of the prefrontal cortex-habenula pathway was correlated with earlier age of first drug use.

Image shows a woman's hand holding a cigarette.

Featured Open Neuroscience Articles Psychology

·March 1, 2016·5 min read

Why Adolescents Are More Vulnerable to Addiction

A new study explores why teens may be more vulnerable to addiction than adults.

Image shows a person holding their head.

Featured Psychology

·June 17, 2016·5 min read

‘Carrots and Sticks’ Fail to Change Behavior in Cocaine Addiction

A new study might help to explain why people continue to take drug, even though they are aware of the negative consequences and why they find their behavior so hard to change.

Featured Neuroscience Open Neuroscience Articles

·July 23, 2020·4 min read

Mysterious Brain Structure Sheds Light on Addiction

A new study reveals the role the claustrum plays in cocaine addiction. Inhibiting claustral neurons prevented behavioral responses to cocaine in mouse models of addiction.

Featured Genetics Neuroscience

·April 9, 2020·4 min read

Novel role for dopamine that impacts gene expression related to cocaine abuse discovered

Reducing H3Q5dop in rat models of cocaine withdrawal significantly reversed cocaine mediated gene expression changes and reduced cocaine-seeking behaviors.

Featured Genetics

·July 13, 2018·3 min read

Maged1 Gene Protects Against Cocaine Addiction

A new study reports mice lacking the Maged1 gene are unable to acquire an addiction to cocaine.

Featured Genetics Neuroscience

·September 17, 2018·5 min read

Gene Therapy Via Skin Protects Mice From Lethal Cocaine Doses

Using CRISPR gene editing techniques, researchers create modified skin grafts that rapidly degrade cocaine and reduce drug seeking behaviors in mouse models of addiction.

Image shows a woman and shattered glass.

Featured Neuroscience

·June 27, 2017·5 min read

Reprogramming Brain Region Can Suppress Cocaine Cravings: Mouse Study

Silencing pyramidal neurons in the infralimbic cortex made rats more likely to relapse than those that underwent withdrawal from cocaine. The findings support growing evidence that the infralimbic cortex plays a vital role in suppressing addictive behaviors.

Featured Genetics Neuroscience

·September 2, 2019·3 min read

Chronic cocaine use modifies gene expression

Chronic cocaine use alters the epigenetic profile of the FosB gene in the hippocampus. These alterations are required for cocaine-dependent gene expression and cocaine environment associations. Modification of hippocampal FosB results in a condition critical for cocaine-related learning.