Researchers report microglia, immune cells found in the brain, may trigger overeating and increase weight gain as a response to high fat diets. The study suggests targeting microglia could provide new treatment options to help curb obesity.
A new study reveals how autophagy in certain immune cells can lead to the immune system attacking the central nervous system. The findings have implications for the treatment of autoimmune diseases, like multiple sclerosis.
Using a mathematical model based on experimental data from multiple sclerosis patients, researchers performed computer simulations of the different known biological processes associated with the disease. They discovered the symptoms and disease course are produced by the same underlying mechanism that damages the nerve cells over time.
Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.