A new study reveals the role the claustrum plays in cocaine addiction. Inhibiting claustral neurons prevented behavioral responses to cocaine in mouse models of addiction.
Psilocybin reduces activity in the claustrum, an area of the brain believed to contribute to consciousness and sense of self. Researchers say the reduced activity may tie in with the reduced sense of self and ego often associated with psychedelic drug use. The study also reports psilocybin alters the way the claustrum communicates with brain areas involved in attention, decision making, auditory processing, and memory.
Mouse study reveals slow-wave brain activity, which is indicative of sleep and resting states, is controlled by the claustrum. The synchronization of active and silent states across the brain via the slow waves contributes to consciousness.