Chronic stress which involves the HPA axis may contribute to the development of Alzheimer's disease, researchers report.
Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check.
Rats susceptible to anhedonia have more serotonin neurons in the ventral dorsal raphe nucleus. However, activating neurons in the central amygdala reduced the serotonin signaling and lowered the effects of social stress.
Deep sleep restores the medial prefrontal cortex mechanisms that restore emotion. This lowers emotional and physiological reactivity, preventing the escalation of stress and anxiety.
Early life stress alone impairs hippocampal development. Stress, in addition to maternal mistreatment within the first few weeks of life, also hinders amygdala development.
Chronic stress during pregnancy increases neuroinflammation. The immune changes may create circumstances in the brain, which increase susceptibility to postnatal depression.
A new study identifies a novel neural network regulating feeding and mood in response to chronic stress. Inhibiting the POMC to ventral tegmental area circuit increases body weight and food intake while reducing depressive symptoms in mouse models.
Chronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.
A new study reports teens faced with chronic family stress have higher blood pressure and worse immune response to bacterial infections. However, those who used cognitive reappraisal had lower blood pressure, despite the pressures they faced.
Researchers have identified a new neural mechanism that contributes to long term stress and PTSD. The study reports the mechanism is mediated by brain fluid in areas associated with stress response.