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chronic pain

Featured Psychology

·January 12, 2016·5 min read

Increased Risk of Depression Linked to Long Term Opioid Use

According to a new report, long term use of opioid for pain can increase the risk of patients developing depression.

Featured Neurology Neuroscience Pain

·June 30, 2026·11 min read

Does Melatonin Help Reduce Chronic Pain?

Melatonin can reduce chronic musculoskeletal pain by 9 to 10 points on a 100-point scale. This therapeutic relief matches the efficacy of opioids and NSAIDs while bypassing their severe risks of organ toxicity and addiction, offering a safe, non-dependent adjunct that treats pain and sleep disruption simultaneously.

Featured Neurology Pain

·April 22, 2023·5 min read

Alcohol Fuels Pain: Study Reveals Link Between Drinking and Chronic Pain

Chronic alcohol consumption can increase sensitivity to pain through two molecular mechanisms. Researchers also identified potential new drug targets for treating alcohol-related chronic pain. Over half of people with alcohol use disorder (AUD) suffer from persistent pain, including alcoholic neuropathy. The study found that alcohol withdrawal could result in neuropathy that was not reversed by re-exposure to alcohol.

This shows a woman clutching her tummy in pain

Featured Genetics Neurology Open Neuroscience Articles Pain

·April 9, 2021·3 min read

Higher Rates of Chronic Pain in Women Linked to Genetics

Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.

Featured Neurology Open Neuroscience Articles Pain

·February 13, 2019·7 min read

Breakthrough in Developing Blood Test for Pain

Researchers have identified biomarkers in the blood which can help determine the severity of a person's pain level. The findings could help doctors to accurately measure pain and stem the opioid crisis.

Outline of a person with pain points highlighted.

Featured Neurology Pain

·October 12, 2015·4 min read

Chronic Pain is in the Brain

A new study reports on the role of HCN channels in pain processing.

This shows a person holding their head in pain.

Featured Neurology Neuroscience Pain Psychology

·March 19, 2026·9 min read

Why Chronic Pain Leads to Depression

New research reveals that the hippocampus acts as a control center for chronic pain, and a specific "inflammatory switch" determines who develops depression.

Featured Neurology

·May 10, 2018·5 min read

Neuroinflammation Seen in Spinal Cord and Nerve Roots of Patients With Chronic Sciatica

A new study reveals a link between chronic sciatica and inflammation in key areas of the nervous system. Researchers say the location of the inflammation could help to determine which patients will feel relief from steroid injections to curb the pain.

Featured Neurology Neuroscience Open Neuroscience Articles Pain Psychology

·January 10, 2019·6 min read

Men and Women Remember Pain Differently

A new study reports males seem to remember experiences of pain more clearly, while females are less stress by previous painful experiences. Researchers injected ZIP, a memory blocker into the brains of mice before a painful experience. Following the treatment, the males showed no signs of remembering the pain. The study suggests chronic pain is a problem to the extent you remember it. The findings could help develop new treatments for chronic pain.

Featured Neurology Neuroscience Pain

·August 20, 2024·3 min read

Molecule Discovery Could Revolutionize Chronic Pain Treatment

Researchers have identified a natural molecule, phosphatidic acid, that reduces the sensitivity of touch-sensing ion channels, providing a promising new avenue for managing chronic pain. By increasing levels of this molecule, cells become less sensitive to touch, which was confirmed through tests on sensory neurons and in mice. This discovery could lead to more targeted and effective treatments for conditions involving inflammatory pain.

Featured Psychology

·November 5, 2013·3 min read

Torture Permanently Damages Normal Perception of Pain

Prisoners of war experience dysfunctional perception and regulation of pain many years after their release. Researchers believe this could be a result of torture they received while incarcerated.