Brain structure abnormalities could predispose people to chronic pain following a lower back injury, researchers suggest.
Could rethinking the way we think about chronic pain curb the growing epidemic of opioid addiction?
M2 macrophages can produce various endogenous opioids, such as endorphins, enkephalin, and dynorphin, which activate opioid receptors at the site of inflammation.
Neuroimaging study reveals people who report widespread pain have increased gray matter and functional connectivity in sensory and motor areas of the brain.
The findings in fruit fly larvae demonstrate the first known function for the sensory neurons and provide insights that could broaden the understanding of chronic pain syndromes in humans.
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Researchers have begun to work on a new closed loop system which will treat diseases by modulating the activity of peripheral nerves.
Researchers have uncovered a neurological mechanism that may contribute to the reduction of chronic pain.
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People suffering from chronic pain pay more attention to pain related words than those who are pain free, a new study reports.
Researchers use a wireless electrical device to stimulate deep brain areas and provide relief for chronic pain.
Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.
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A white paper from the NIH reports little to no evidence for the effectiveness of opioid drugs in treating long term chronic pain.
Researchers report THC oil may be beneficial in providing pain relief for those suffering radicular pain, such as sciatica. The study reports marijuana reduces connections between areas of the brain that process sensory signals and emotions.