A new study reveals the prefrontal cortex may play a role in coordinating the level of consciousness through the cholinergic system.
Researchers have developed a new neuroimaging method to track neurodegeneration in Alzheimer's disease. The method helped uncover a new pathway for how degeneration spreads from one brain region to another.
Researchers report when mice bred to display Alzheimer's like symptoms were given diets high in choline, their offspring showed improvements in spatial memory compared to those exposed to normal levels of choline in the womb.
Choline, an essential nutrient, can help prevent fetal brain development problems in infants whose mothers experience common infections, such as influenza, during pregnancy.
Preterm babies who were fed breastmilk had significantly higher levels of creatine and choline, key metabolites for brain growth and development, than those who were formula fed.
Maternal cannabis negatively impacts fetal brain development at an early stage of pregnancy than was previously believed. However, increasing choline consumption, either through diet or supplementation, could help protect the developing brain from potential harm.
Adding extra choline through eggs or meat to your daily diet could help stave off the effects of dementia. Higher phosphatidylcholine intake through diet was associated with lower rates of dementia and improved cognitive function in aging men.
POMC, a gene which regulates the stress response system, and PER2, a gene associated with circadian regulation, are altered in women who drank moderate-to-high amounts of alcohol during pregnancy and their newborns.
Taking dietary choline supplements may help to protect the brain from Alzheimer's disease. Choline reduces the activation of microglia which, when overactivated, contribute to neuroinflammation and apoptosis associated with Alzheimer's. Choline also helps block the production of amyloid plaques.
Findings show sex-specific baizes in gene expression changes and demonstrate cellular control mechanisms based on microRNA change. The study sheds new light on genetic and neurological changes associated with schizophrenia and bipolar disorder.