A preclinical drug that inhibits the kinase enzyme Cdk5 may have the potential to treat depression, brain injuries, and disorders associated with cognitive impairment.
Cortical and subcortical memory regions exhibit distinct genetic signatures that reflect potential differences in health and disease.
High-fat diets during pregnancy may protect the developing brain from Alzheimer's in those with genetic risk factors.
A new mouse study reveals males recall fearful memories better than females. Researchers attribute the difference to the gene Cdk5, which has previously been implicated in creating fear memories and stress behaviors. The study reports Cdk5 is naturally activated in males, but not females.
According to a new study, the immune system may play a critical role in damage associated with neurodegenerative disorders such as Alzheimer's disease and ALS. The study reports altering Cdk5 results in the death of dopamine neurons and slowed autophagy.
A new study reveals neurodegenerative diseases may speed up the aging process.
A new study sheds light on the mechanisms of gyrus formation.
A new study reports AIS plasticity happens quickly, influencing the way cells fire action potentials.
Researchers claim they have learned to fix the Golgi structure which becomes fragmented in patients with AD.
Using well known mouse models, researchers demonstrate a potential new target to fight Alzheimer's and other neurodegenerative diseases.
A modified form of the enzyme Cdk5 is elevated in the brains of Alzheimer’s disease patients, where it triggers damage...
