During memory tasks, people with psychosis have different patterns of activity in the prefrontal and mediotemporal brain areas compared to those without the disorder. When exposed to cannabidiol (CBD), the activity of the brain areas became more like those seen in the controls for people with psychosis. Patients reported a decrease in symptoms of psychosis following one dose of CBD. Researchers stress that no definitive conclusions could be made about the effectiveness of CBD use over a sustained period.
The effect cannabidiol has on Lennox-Gastaut syndrome may be explained by the drug-drug interaction between CBD and anti-seizure medication.
Brain and fetal development damage caused by exposure to CBD and THC are very similar defects seen in fetal alcohol syndrome.
Pure CBD products will not cause a positive drug test, but low-THC/high-CBD products may trigger a positive drug test for some users.
Every month, up to 6.4 million searches related to cannabidiol (CBD) are performed by American adults looking to obtain information or buy products. CBD search queries eclipse those for other natural medical alternatives by a significant percentage.
Introducing and prescribing standard units for cannabis, which make people aware of the concentrations of THC in the product, could help improve mental health treatments and outcomes.
CBD blocks the ability of THC to overstimulate the ERK pathway in the hippocampus, preventing negative side effects associated with cannabis use.
CBD, which is a major phytocannabinoid constituent of cannabis, has already shown to have anti-epileptic, anti-anxiety, and anti-psychotic effects. The image is in the public domain.
Marijuana use alters a gene associated with autism in sperm. Hypomethylation was identified in the DLGAP2 gene in the sperm of male rats exposed to THC. The hypomethylated state was also detected in the forebrains of their offspring. Further research is needed to establish if there is a definitive link between paternal cannabis use and ASD in humans.
37% of Millenials and 25% of Gen Xers say they have used cannabinoids to help relieve pain.
People who used while dried cannabis flowers or cannabis with higher levels of THC had the greatest analgesic response to pain. Those who used CBD reported lower levels of pain relief.