A study using rat models of depression reveals a single dose of the cannabis extract CBD can help to reduce symptoms of depression for up to one week. Researchers say cannabidiol appears to activate mechanisms that help repair neural circuitry in the prefrontal cortex and hippocampus, which get damaged as a result of depression.
A new study reveals cannabinoid medications may not reduce pain itself, but instead make pain feel less unpleasant and more tolerable.
A new study reveals long term alcohol use is much more damaging to the brain than marijuana. Researchers reveal long term alcohol use is linked to a decrease in both white and gray matter integrity in the hippocampus. However, no such decrease is associated with long term cannabis use.
Researchers report amnesia caused by cannabinoids relies on the activation of the CB1 receptor in mitochondria in the hippocampus.
A new study finds THC reduces amyloid beta proteins in human neurons.
Researchers report brain alterations associated with heightened feelings of negative emotion and alienation in people who have a dependence on cannabis.
People with the specific genotype of the Cannabinoid receptor 1 gene may be more prone to cannabis use disorder. Researchers report those with FAAH rs324420 A continue to want more marijuana following use and are more drawn to cannabis-related imagery while under the influence of the drug.
A new study seeks to better understand how cannabis use alters the oral microbiome and how this may have an impact on neurodegenerative disorders.
In-vitro exposure to THC can cause birth defects in genetically predisposed mice. THC interferes with Hedgehog signaling in the developing mice, leading to an increased risk of birth defects.
Cannabigerol (CBG), a non-psychoactive cannabis compound, has antibiotic potential. Treating mice with MRSA, CBG worked as well as vancomycin, a powerful antibiotic, for treating the infection.
According to researchers, Cannabidiol, an active compound in cannabis plants, could help to alleviate cognitive impairment in people with schizophrenia.
A new study reveals CBD oil may help to reduce, or even eliminate seizures, in those with epilepsy.