Cannabidiol, or CBD, blocks the ability of lysophosphatidylinositol (LPI) to amplify neural signals in the hippocampus. LPI weakens the signals that counter seizures, further explaining the value of CBD to treat epilepsy.
Study finds no evidence that cannabidiol (CBD) reduces the negative effects of cannabis.
Cannabidiol treatment helped reduce anxiety severity by, on average, 42.6% in young adults with treatment-resistant anxiety, a new study reports.
Cannabidiol (CBD) simultaneously acts on two targets in pain-sensing neurons. Researchers are developing new drugs that have similar actions to CBD that may be better absorbed by the body.
Cannabinol, an active ingredient in cannabis, can help protect brain cells from oxidative damage and preserve mitochondrial function.
Cannabis terpenes, the part of the plant which provides aroma and flavor, may provide therapeutic benefits in controlling pain, a new study reports.
A newly developed cannabidiol capsule can be absorbed by the body faster and penetrate the brain more quickly in mouse models of neurological disorders such as Alzheimer's disease, multiple sclerosis and TBI.
KLS-13019, a novel CBD analog, shows promise at reversing pain sensitivity and preventing symptoms of neuropathy in mouse models of chemotherapy-induced peripheral neuropathy.
CBD does not appear to reduce experimental pain intensity but does make the experience of pain less unpleasant.
Cannabidiol (CBD) increases cerebral blood flow to areas of the brain associated with memory processing, specifically the hippocampus. The findings identify a potential mechanism for the use of CBD to treat disorders associated with altered memory processing, including Alzheimer's disease, PTSD, and schizophrenia.
Cannabidiol (CBD) appears to slow the growth of glioblastoma brain cancer cells in both animal and human cell lines. CBD's anti-cancer actions target mitochondria, causing them to dysfunction and release harmful reactive oxygen species. Cancer cells treated with CBD exhibited significant decreases in mitochondrial activity.
Using purified botanical cannabidiol (CBD) to treat mouse models of Davet syndrome improved mortality and reduced behavioral symptoms associated with the condition.
