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CA1

·March 14, 2019·5 min read

Brain Wave Stimulation May Improve Alzheimer’s Symptoms

Multisensory gamma wave stimulation improves recognition and spatial memory, in addition to reducing amyloid in the auditory cortex and hippocampal CA1 areas of mice. Findings suggest such sensory stimulation boosts hippocampal function and reduces Alzheimer's linked pathologies throughout the neocortex.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 9, 2020·4 min read

Brain-doping produced by your own body

Cognitive challenges trigger a slight oxygen deficit in hippocampal pyramidal neurons. This increases the production of erythropoietin (Epo) and its receptors in the active neurons, stimulating neighboring precursor cells to form new neurons and enhancing connectivity.

Featured Neuroscience

·January 13, 2018·4 min read

Brain’s GPS Has a Buddy System

A new study by Riken researchers reveals how the hippocampus is able to maintain a mental map of both a rat's location and the movements of other rats close by.

Image shows a brain and marijuana leaves.

Featured Neuroscience Open Neuroscience Articles

·September 23, 2017·4 min read

Breaking Memory Circuits With Marijuana

New research reveals the dynamics of neural circuits under the influence of cannabinoids.

This is a drawing of the hippocampus with CA3, CA1 and the DG labeled.

Electrophysiology Featured Neuroscience

·March 30, 2015·3 min read

Building Block for Memory and Learning Identified

Researchers discover a key receptor which is responsible for activating opposing forms of plasticity in the hippocampus.

Image shows the CA1 area of the hippocampus highlighted in a mouse brain.

Featured Neuroscience

·January 18, 2016·5 min read

Cellular Diversity in the Hippocampus

Researchers have discovered an unexpected diversity within CA1 pyramidal neurons in the hippocampus.

Image shows fish made out of omega 3 fish oil pills.

Featured Neurology

·July 18, 2017·4 min read

Could Omega 3 Fatty Acids Help Treat Alzheimer’s?

Researchers shed new light on how DHA, a key essential Omega-3 fatty acid, could help promote cell survival and contribute to treating Alzheimer's, Parkinson's disease and stoke.

Featured Neuroscience

·September 23, 2019·2 min read

Critical role of brain circuits in improving learning and memory revealed

A newly identified neural network in the hippocampal formation plays a critical role in memory and object-location learning. The findings are highly relevant to learning and memory disorders, including Alzheimer's disease.

Image shows a diagram of the hippocampus.

Featured Neurology

·October 16, 2017·6 min read

Dietary Supplement Dampens Brain Hyperexcitability Seen in Epilepsy

Researchers were able to dampen hyperexcitability associated with seizure disorders in rodent models by inducing biochemical alterations with glucosamine, a dietary supplement.

Electrophysiology Featured Neuroscience

·October 8, 2012·2 min read

Discovery of Gatekeeper Nerve Cells Explains the Effect of Nicotine on Learning and Memory

Researchers discovered a new group of nerve cells that regulate processes of learning and memory. These cells act as gatekeepers and carry a receptor for nicotine, which can help explain our ability to remember and sort information. The newly discovered gatekeeper nerve cells, also called OLM-alpha2 cells, provide an explanation to how the flow of information is controlled in the hippocampus.

This shows a finger touching a picture of a brain

Featured Neuroscience Open Neuroscience Articles

·September 16, 2021·3 min read

Drug Targets for Memory Enhancement

Researchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.