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          C9ORF72

          This is a cross section MRI of a patient with ALS.
          FeaturedGeneticsOpen Neuroscience Articles
          ·October 16, 2013·6 min read

          ‘Individualized’ Therapy for the Brain Targets Specific Gene Mutations Causing Dementia and ALS

          Using neurons created from iPS cells derived from people with ALS, researchers develop a new drug which appears to halt the impact of the genetic mutations in some forms of ALS and dementia.
          Read More
          The image is an autopsy specimen of a patient with frontotemporal dementa.
          FeaturedGenetics
          ·October 25, 2013·5 min read

          Lou Gehrig’s Disease: From Patient Stem Cells to Potential Treatment Strategy in One Study

          Researchers create neurons from the skin cells of ALS patients in order to "treat" a gene defect in a dish.
          Read More
          The image shows frontotemporal degeneration in the brain.
          FeaturedNeurologyOpen Neuroscience Articles
          ·October 30, 2013·3 min read

          RNA Build Up Linked to Dementia and Motor Neuron Disease

          Researchers have identified a new toxic entity associated with genetically inherited forms of frontotemporal dementia and motor neuron disease.
          Read More
          This image shows a motor neuron which was created from stem cells.
          FeaturedGenetics
          ·March 6, 2014·4 min read

          3D Changes in DNA May Lead to a Genetic Form of ALS

          Researchers discover how a genetic code variation in the C9orf72 gene alters the shape of DNA, making cells more vulnerable to stress and apoptosis.
          Read More
          The image shows the brain of an adult fruit fly.
          FeaturedGeneticsNeurology
          ·August 12, 2014·2 min read

          Toxic Proteins Damage Nerve Cells

          Researchers discover how a specific genetic mutation leads to neuronal damage associated with ALS and frontotemporal dementia.
          Read More
          Scientists created a mouse model of ALS and FTD caused by mutations in the C9ORF72 gene. Credit: Courtesy of Petrucelli lab, Mayo Clinic, Jacksonville, Fla.
          FeaturedGenetics
          ·May 22, 2015·4 min read

          Scientists Create Mice with a Major Genetic Cause of ALS and FTD

          Researchers believe mouse could provide a new platform for testing treatments for several neurodegenerative diseases.
          Read More
          This shows neurons created from an ALS patient.
          FeaturedGeneticsNeurology
          ·August 26, 2015·6 min read

          RNA Blocked Pathways May Initiate ALS and Dementia

          According to new research, the C9orf72 mutation causes long strands of RNA to block specific pathways which usually move proteins into a cell's nucleus.
          Read More
          Image shows antibodies surrounding a healthy motor neuron.
          FeaturedNeurology
          ·October 5, 2015·4 min read

          Tracking a Key Piece of Dementia and ALS Puzzle

          Findings provide new hope for treating ALS and FTD, researchers report.
          Read More
          Genetically mutated cell.
          FeaturedGeneticsNeurology
          ·October 19, 2015·4 min read

          ALS and Frontotemporal Dementia Linked to Nuclear Transport Problems

          A new study points to a potential new target to treat neurodegenerative diseases.
          Read More
          Image shows a brain against a DNA double helix background.
          FeaturedGeneticsNeurology
          ·March 17, 2016·4 min read

          Immune Cells Play Direct Role in Development of ALS

          Immune cells appear to play a direct role in the development of ALS, a new study reports.
          Read More
          lymphoid tissue
          FeaturedNeurology
          ·July 15, 2016·4 min read

          Reopening Avenues for Attacking ALS

          Researchers report the most common genetic mutation associated with ALS plays an important role in not only the nervous system, but also the blood and immune systems.
          Read More
          Image shows a hippocampal slice.
          FeaturedGeneticsNeurology
          ·August 1, 2016·4 min read

          New Areas of the Brain Identified Where ALS Gene is Active

          Researchers report they have identified two regions of a mouse brain where a gene implicated in ALS is expressed.
          Read More
          1 2 3

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          This shows a child's head.

          Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

          This shows a donut.

          Ultra-Processed Foods: AI’s New Contribution to Nutrition Science

          This shows neurons.

          Aging Myelin: A New Perspective in Alzheimer’s Disease Progression

          This shows a head and brain.

          Promising Phase 2 Trial Results for Pembrolizumab in Metastatic Brain Cancer

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