FeaturedGeneticsNeurosciencePsychology·May 19, 2026·15 min readPeripheral White Blood Cells Fuel SchizophreniaA new study reveals that neutrophils, the body's most common white blood cells, act as hidden factories for C4A, the single strongest common genetic risk protein linked to schizophrenia.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology·November 3, 2022·3 min readInflammation May Amplify Effect of Genetic Risk Variants for SchizophreniaPro-inflammatory cytokines IL-1 beta and IL-6 stimulate the expression of the schizophrenia-related C4A gene. Patients with high C4A expression displayed increased levels of IL-1 beta in cerebral spinal fluid samples. C4A levels were also correlated with markers of synaptic density. Findings reveal inflammation enhances the genetic risk variant for schizophrenia.Read More
FeaturedGeneticsNeuroscience Videos·January 27, 2016·5 min readStrongest Genetic Risk for Schizophrenia DeconstructedA gene associated with schizophrenia may trigger runaway synaptic pruning during adolescence, a new study reports.Read More
