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          Brigham and Women’s Hospital

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          FeaturedNeurologyNeuroscience
          ·May 29, 2024·6 min read

          Early Memory Complaints Linked to Alzheimer’s Brain Changes

          A new study finds that reports of cognitive decline from patients and their partners are linked to the accumulation of tau tangles, a hallmark of Alzheimer's disease. This underscores the importance of addressing memory concerns early.
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          FeaturedNeurologyNeuroscience
          ·March 20, 2024·4 min read

          Astrocytes Remember: A New Layer of Immune Memory Uncovered

          Astrocytes, traditionally non-immune cells within the central nervous system, possess the ability to develop an immune memory, responding more vigorously to subsequent immune challenges. This groundbreaking study reveals that through an epigenetic mechanism involving the enzymes p300 and ATP-citrate lyase (ACLY), astrocytes enhance their pro-inflammatory responses, a trait similar to the immune memory seen in adaptive immunity.
          Read More
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          FeaturedGeneticsNeurologyNeuroscience
          ·December 5, 2023·3 min read

          Brain Cell Genetics Illuminate Alzheimer’s Disease Pathways

          Researchers made a significant advance in understanding Alzheimer's disease (AD) by pinpointing how specific brain cells contribute to different stages of the disease. Employing single nucleus RNA sequencing, they analyzed genetic risks in microglia and astrocytes, revealing distinct roles these cells play in AD progression.
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          FeaturedNeurosciencePsychology
          ·October 19, 2023·5 min read

          Microbiome and Diet Could Mitigate PTSD Symptoms

          Researchers explored the potential link between the Mediterranean diet, the gut microbiome, and PTSD symptoms. Their study, involving 191 participants, revealed that those following a Mediterranean diet exhibited fewer PTSD symptoms.
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          FeaturedNeuroscience
          ·October 2, 2023·6 min read

          Sleep Struggles Link to Elevated Risk of Hypertension

          Researchers have found a notable link between insomnia symptoms and hypertension in women. Drawing from a 16-year study involving over 66,000 participants, the study showed women with sleep difficulties were more prone to high blood pressure.
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          FeaturedNeuroscience
          ·September 25, 2023·6 min read

          Addiction’s Common Ground: A Universal Brain Circuit Revealed

          Researchers discovered a universal brain network present in people with substance use disorders. Analyzing data from over 144 studies involving 9,000+ participants, they found consistent abnormalities regardless of substance or lesion location.
          Read More
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          Brain CancerFeaturedNeuroscience
          ·September 6, 2023·6 min read

          Rice-Sized Device Tests 20-Plus Brain Cancer Treatments at Once

          Researchers developed a minuscule device, akin to a grain of rice in size, that can simultaneously test numerous treatments for challenging brain cancers like gliomas. Implanted into a patient's tumor during surgery and removed afterward, the device offers real-time insights on drug effects on the tumor microenvironment.
          Read More
          This shows a man's head.
          FeaturedNeurologyNeurosciencePsychology
          ·July 5, 2023·5 min read

          Redefining Depression: TBI Affective Syndrome Discovered

          The study proposes a new term for this variant of depression - “TBI affective syndrome”. Fundamentally, this research marks a significant step toward personalized treatment strategies for TBI patients.
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          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·July 3, 2023·7 min read

          Hidden Brain Circuit Linking Lesion Locations to Epilepsy

          Researchers discovered a shared brain circuit that may link diverse lesion locations that cause epilepsy. The study, which analyzed data from over 1,500 patients with brain lesions, utilized a technique called lesion network mapping.
          Read More
          This shows women's heads.
          FeaturedNeurosciencePsychology
          ·June 10, 2023·3 min read

          Unmasking Anosognosia: Revealing Hidden Brain Networks in Unawareness

          Researchers identified specific brain network connections associated with anosognosia, a condition where patients are unaware of their neurological or psychiatric deficits. Using a technique called lesion network mapping, they identified separate networks linked to visual and motor anosognosia and a shared network responsible for awareness of these deficits. The shared network converged on the hippocampus and precuneus, both associated with memory.
          Read More
          This shows the outline of a head.
          FeaturedNeuroscience
          ·May 24, 2023·6 min read

          Multivitamins Linked to Better Memory and Slower Cognitive Aging

          A new study suggests daily multivitamin supplementation could improve memory among older adults. The study tested the impact of multivitamins on cognitive function. Compared to a placebo group, participants taking daily multivitamins showed significantly better memory performance over a three-year period.
          Read More
          This shows a woman holding her stomach
          FeaturedNeurosciencePsychology
          ·April 27, 2023·6 min read

          Is Your Emotional Wellbeing Related to Your Gut Health? New Study Reveals Possible Link in Women

          Gut bacteria have been linked to positive emotions, such as happiness and hopefulness, and good emotion management skills. Researchers have discovered that people who suppress their emotions have a less diverse gut microbiome, while people who report happier emotions have lower levels of certain bacterium.
          Read More
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          The Ancient Biology Behind the Modern Obesity Crisis

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          3D-Printed “Honeycomb” Sensors Match Your Unique Neural Map

          This shows a brain.

          Glutathione Prevents Cellular Clogs

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          Cortisol Kill-Switch: Exercise Rewires Stress Biology

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