Elevated levels of PHGDH in the blood could signal the earliest stages of Alzheimer's disease. Researchers caution older adults against using "brain-boosting" supplements that contain serine due to its link to PHGDH. As PHGDH is a key enzyme in serine production, elevated PHGDH levels results in increased serine levels in the brain.
Supplements marketed to promote 'brain health' often overstate the products' benefits and do little-to-nothing to improve the aging brain. Researchers investigate the hidden dangers and false claims behind these products, which are highly profitable for manufacturers, but not so beneficial for consumers.