Brain CancerFeaturedNeurologyNeuroscience·April 6, 2019·4 min readNew hope for treating childhood brain cancerDIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.Read More
FeaturedGeneticsNeurologyNeurosciencePsychology·April 1, 2019·3 min readDepression, obesity, chronic pain could be treated by targeting the same key proteinResearchers have developed a compound that blocks the FKBP51 protein, which helps reduce chronic pain, provides positive outcomes for diet-induced obesity and improves symptoms of depression.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 31, 2019·4 min readNew glioblastoma vaccine shows promising results in phase Ib clinical trialA new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 22, 2019·4 min readNew drug combination shows promise for common pediatric brain tumorCombining carboplatin, a common chemotherapy drug, with everolimus, a drug that blocks mTOR, is effective at inducing apoptosis and slowing tumor growth in patients with pediatric low-grade glioma brain cancer.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 6, 2019·5 min readRadiation After Surgery Triples Survival for Ependymoma, a Type of Pediatric Brain TumorA study shows that postoperative radiation improves outcomes for children with ependymoma, even those with historically poor prognoses and the very young.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·February 11, 2019·5 min readImmunotherapy Can Be Effective in Treating People with Recurrent GlioblastomaResearchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 25, 2019·4 min readThe Hitchhiker’s Guide to Defeating GlioblastomaResearchers have developed a new approach that uses microRNA in combination with chemotherapy to help treat glioblastoma brain cancer. In preclinical models, the approach increases survival of the deadly brain cancer five fold.Read More
Brain CancerFeaturedGeneticsNeurologyOpen Neuroscience Articles·January 23, 2019·5 min readTargeted Treatment Shrinks Deadly Pediatric Brain Cancer TumorsResearchers report a targeted therapy that blocks LSD1 effectively shrinks tumor size in mouse models of medulloblastoma, a form of pediatric brain cancer.Read More
FeaturedGeneticsNeurologyNeuroscience·January 20, 2019·3 min readEvaluating the Effects of Environmental Exposures on Neurological DisordersResearchers have identified a number of environmental factors, including the herbicide Linuron, as inflammation activators in neurodegenerative disorders.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 14, 2019·4 min readHerpes Virus and Tumors Evolved to Learn How to Manipulate the Same Ancient RNAA new study reports herpes virus utilizes ancient RNA to proliferate, mimicking the same process tumors have been found to manipulate. The findings could have implications for new treatment options and also may shed light on neurodegenerative diseases.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·January 11, 2019·6 min readA Patient’s Sex Matters When it Comes to Brain CancerResearchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.Read More
Brain CancerFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·January 10, 2019·4 min readNew Immune System Regulators RevealedUsing CRISPR gene editing, researchers mapped important genes for helping T helper cells. The findings could help generate new treatments to activate the immune system against infection and to attack tumor cells.Read More
