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blood-brain barrier

·December 17, 2022·5 min read

Why Does the Alzheimer’s Brain Become Insulin-Resistant?

Insulin binding receptors are predominantly located in the microvessels within the blood-brain barrier. In patients with Alzheimer's, the abundance of these receptors is decreased. This decrease could lead to the loss of insulin response in the Alzheimer's brain.

Featured Genetics Neurology Neuroscience

·November 22, 2022·4 min read

Gene-Delivering Viruses Reach the Brain in Step Toward Gene Therapy for Neurological Diseases

Researchers have developed a family of adeno-associated viral vectors (AAVs) that are able to cross the blood-brain barrier to deliver gene therapies directly to the brain.

Brain Cancer Featured Neuroscience

·November 16, 2022·8 min read

Implanted Pump Safely Delivered Chemo Straight to the Brain in Patients With Brain Cancer

A new implantable pump system safely and effectively bypasses the blood-brain barrier to deliver chemotherapy drugs to those with glioblastoma brain cancer.

Featured Neurology Neuroscience

·August 15, 2022·6 min read

New Role for Blood-Brain Barrier in Neuron Function and Damage

The signals that originate in the cells of the blood-brain barrier also play a direct role in controlling what happens to the neurons the barrier is protecting.

Brain Cancer Featured Neuroscience

·June 1, 2022·5 min read

Engineers Develop Nanoparticles That Cross the Blood-Brain Barrier

Researchers have developed drug-carrying nanoparticles that cross the blood-brain barrier, allowing for more effective delivery to the brain than conventional medications. The nanoparticles can get into tumors and kill glioblastoma brain cancer cells.

This shows tissue macrophages in a mouse brain

Featured Genetics Neuroscience

·April 22, 2022·4 min read

New Discoveries About the Origin of the Brain’s Immune System

New findings reveal phagocytes do not fully mature until after birth, contradicting previous assumptions that they mature during embryonic development.

This shows the outline of a head filled with cogwheels and a lightbulb

Featured Neurology Neuroscience

·April 8, 2022·5 min read

Alzheimer’s Brain Barrier Damage Theory Could Pave Way for New Treatments

Lipids entering the brain as a result of damage to the blood-brain barrier may be a determining cause of Alzheimer's disease. Researchers say simple lifestyle changes could reduce Alzheimer's risks by reducing the impact on the BBB and decrease Alzheimer's associated brain damage.