Reduced levels of an amino acid called betaine is associated with schizophrenia pathology. Supplementing betaine levels improved cognitive and behavioral deficits in mouse models of schizophrenia. The amino acid also reduced oxidative stress at the molecular level.
Betaine, a dietary supplement extracted from sweet beets, reduces behavioral symptoms of schizophrenia in mice with genetic risk factors for the disorder. The supplement may help protect proteins that build the cellular skeletons of neurons.