Latest

beta-amyloid

The image shows neurofibrillary tangles associated with Alzheimer's.

·June 26, 2013·3 min read

Alzheimer’s Disease Mouse Models Point To A Potential Therapeutic Approach

Using well known mouse models, researchers demonstrate a potential new target to fight Alzheimer's and other neurodegenerative diseases.

The image shows a diagram of neurons and an insert which shows how a synapse works.

Featured Neurology

·June 25, 2013·3 min read

Protein Linked to Cognitive Decline in Alzheimer’s Identified

Caspase-2 is a key regulator of a signaling pathway which leads to cognitive decline in Alzheimer's disease, a new study finds.

Featured Neuroscience

·June 24, 2013·4 min read

NMR Advance Brings Proteins into the Open

Researchers combine data from four different NMR techniques to observe chaperone GroEL capture a disordered beta-amyloid protein.

The diagram shows beta amyloid formation in alzheimer's disease.

Featured Neurology

·June 12, 2013·4 min read

Alzheimer’s Brain Change Measured in Humans

Researchers have successfully measured a significant difference between the brains of patients with an inherited form of Alzheimer's disease and their healthy family members who do not carry the genetic mutation for the disease.

The image which shows how enzymes act on Amyloid precursor protein.

Featured Neuroscience

·May 23, 2013·3 min read

Anti-Cancer Drug Viewed as Possible Alzheimer’s Treatment Doesn’t Work in UF Study

Bexarotene, an anti-cancer drug which is about to be tested in a clinical trial as a potential treatment for Alzheimer's disease, fails to reduce amyloid plagues; according to researchers replicating the original study.

The image shows a brain slice with amyloid plaques stained.

Featured Neurology Open Neuroscience Articles

·April 11, 2013·2 min read

New Findings on the Brain’s Immune Cells During Alzheimer’s Disease Progression

As Alzheimer's disease progresses, microglial cells lose two important biological functions affecting their ability to remove cell fragments and motility towards acute lesions.

This is a histopathogic image of senile plaques seen in the cerebral cortex in a patient with presenile onset of Alzheimer disease.

Featured Neuroscience

·March 5, 2013·2 min read

Green Tea Extract Interferes with the Formation of Amyloid Plaques in Alzheimers Disease

Researchers used a specific molecule in green tea extract, EGCG, to control metal associated amyloid beta aggregates associated with Alzheimer's disease and other neurodegenerative disorders.

The image shows 3 diagrams of beta amyloid plaque formations.

Featured Neurology

·February 27, 2013·2 min read

Researchers Identify Possible Treatment Window for Memory Problems

A new study identifies a potential treatment window of several years for plaques in the brain considered to cause memory loss in diseases such as Alzheimer's.

The image shows a chart of the activation and antagonists of NMDA receptors.

Electrophysiology Featured Neuroscience

·February 19, 2013·2 min read

Rewriting a Receptor’s Role

Researchers upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons. The study describes how a compound linked to Alzheimer's disease impacts NMDA receptors and weakens synaptic connections between brain cells.

Featured Neurology

·August 20, 2012·2 min read

Brain Enzyme is Double Whammy for Alzheimer’s Disease

Researchers discover that an enzyme known for generating toxic brain plaques in Alzheimer's disease also causes additional memory and cognitive deficits via a separate mechanism. They found that BACE1 disrupts the cell's production of other molecules required for PKA function. By that mechanism, BACE1 inactivates PKA and therefore inhibits memory formation in mice, even in the absence of neurotoxic β-amyloid.

Featured Neurology

·August 9, 2012·3 min read

Blood Test for Alzheimer’s Gaining Ground

Scientists have taken a step toward developing a blood test for Alzheimer's, finding a group of markers that hold up in statistical analyses in three independent groups of patients.

Featured Neurology

·August 1, 2012·2 min read

Artificial Butter Flavoring Ingredient Linked to Key Alzheimer’s Disease Process

A new study raises concern about chronic exposure of workers in industry to a food flavoring ingredient used to produce the distinctive buttery flavor and aroma of microwave popcorn, margarines, snack foods, candy, baked goods, pet foods and other products. It found evidence that the ingredient, diacetyl (DA), intensifies the damaging effects of an abnormal brain protein linked to Alzheimer’s disease.

1 2 3 4

beta-amyloid

Alzheimer’s Disease Mouse Models Point To A Potential Therapeutic Approach

Protein Linked to Cognitive Decline in Alzheimer’s Identified

NMR Advance Brings Proteins into the Open

Alzheimer’s Brain Change Measured in Humans

Anti-Cancer Drug Viewed as Possible Alzheimer’s Treatment Doesn’t Work in UF Study

New Findings on the Brain’s Immune Cells During Alzheimer’s Disease Progression

Green Tea Extract Interferes with the Formation of Amyloid Plaques in Alzheimers Disease

Researchers Identify Possible Treatment Window for Memory Problems

Rewriting a Receptor’s Role

Brain Enzyme is Double Whammy for Alzheimer’s Disease

Blood Test for Alzheimer’s Gaining Ground

Artificial Butter Flavoring Ingredient Linked to Key Alzheimer’s Disease Process

Protein Key to Lifespan and Healthy Aging Identified

Unlocking Genes Behind Neurodevelopmental Disorders

Placebo Power: Patient Belief in Treatment Impacts Depression Therapy Effectiveness

Redefining Myelin Damage

Subscribe