Turning off kappa opioid receptors in the brain decreases the urge the binge drink. Findings suggest the kappa opioid receptor system is important not only for the negative state of withdrawal but also for driving binge drinking behaviors.
Neurons in the bed nucleus of the stria terminalis (BNST) appear to regulate food intake. The neurons appear to form part of a network that controls appetite loss in mice.
According to researchers, blocking the activity of oxytocin restored normal social behavior in stressed mice.
Researchers report people who experienced emotional abuse and neglect as children exhibited increased amygdala activity in anticipation of a mild electrical shock. The findings suggest early life stress could have an impact on the perception of distant threat.
Researchers have pinpointed the precise cellular connections responsible for triggering overeating.