In the absence of neural activity, BDNF expression can still be activated. The findings shed light on how therapeutic ketamine used has an antidepressant effect and how it works in both the long and short term.
Researchers use a novel co-culturing method to create functional circuits that model Huntington's disease and find new clues to potential treatment approaches.
A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment.
Contradicting previous studies, UC Boulder researchers report there is no clear evidence of any candidate gene associated with depression.
Studying juvenile zebra finches, researchers discover a mechanism which could possibly be responsible for the differences in the intensity of song learning.
Researchers report both negative and positive experiences influence how genetic factors influence the brain and behavior.
SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
Adolescent rats exposed to alcohol had a decrease of both Arc eRNA expression and Arc gene expression in the amygdala during adulthood. Additionally, the alcohol-exposed rats displayed increased anxiety behaviors as they aged.
Researchers have been able to successfully boost the regeneration of mature nerve cells in the spinal cord of adult mice following spinal cord injury.
Researchers from Rockefeller University have identified what they claim to be 'remarkable' differences between the way the male and female brains respond to stress.
A plasma membrane protein affects the generation of new neurons in the adult hippocampus, a new study reports.
