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          BBB

          This shows the outline of a body and a red brain
          FeaturedGeneticsNeuroscience
          ·February 6, 2021·5 min read

          Critical Flaw Found in Lab Models of the Human Blood-Brain Barrier

          Human brain endothelial cells used to generate lab models of the human blood-brain barrier were missing several key proteins found in natural endothelial cells. The cells had more in common with epithelial, a type of cell not normally found in the brain. The findings put into question over a decade worth of lab-based research on the BBB.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·January 1, 2021·5 min read

          Nanoparticle Drug-Delivery System Developed to Treat Brain Disorders

          A new nanoparticle drug-delivery system resulted in unprecedented siRNA penetration across the intact blood-brain barrier. Researchers say the system could help doctors to treat secondary injuries associated with TBI that can result in Alzheimer's and other neurodegenerative disorders.
          Read More
          This shows astrocytes
          FeaturedNeuroscience
          ·September 21, 2020·5 min read

          Advancing Understanding of Blood-Brain Barrier Health

          Study reveals the important role astrocytes play in maintaining blood-brain barrier health.
          Read More
          This shows the drug transportation over the bbb via neurotransmitters
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·July 24, 2020·5 min read

          Novel Drug Delivery Particles Use Neurotransmitters as a ‘Passport’ Into the Brain

          Tufts researchers have developed neurotransmitter-lipid hybrids that help transport therapeutic drugs and gene editing proteins across the blood-brain barrier in mice.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·April 29, 2020·4 min read

          APOE4 triggers early breakdowns in the blood-brain barrier

          APOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's.
          Read More
          This is a diagram from the study
          FeaturedNeuroscience
          ·April 17, 2020·3 min read

          New nanocarrier drug delivery technology crosses the blood-brain barrier

          Researchers have developed a cyclic peptide that can enhance blood-brain barrier penetration.
          Read More
          This is a diagram from the study
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·February 28, 2020·3 min read

          Our own immune cells damage the integrity of the blood-brain barrier

          Microglia initially protects the blood-brain barrier from damage due to systemic inflammation. However, microglia can alter their behavior and increase the permeability of the blood-brain barrier, thus damaging it.
          Read More
          This shows an inflamed brain
          FeaturedNeurologyNeuroscience
          ·December 29, 2019·7 min read

          Drugs that quell brain inflammation reverse dementia

          Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.
          Read More
          This shows brain scans from the study
          FeaturedNeurologyNeuroscience
          ·December 4, 2019·6 min read

          Drugs that quell brain inflammation reverse dementia

          A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice.
          Read More
          This shows the setup of the equipment
          FeaturedNeurologyNeuroscience
          ·June 6, 2019·5 min read

          Ultrasound method restores dopaminergic pathway in brain at Parkinson’s early stages

          Using transcranial focused ultrasound in combination with injectable microbubbles, researchers open a pathway through the blood-brain barrier. The technique allows drugs to penetrate the brain and trigger therapeutic effects for those with neurodegenerative diseases.
          Read More
          This shows the BBB created on the organ-chip
          FeaturedNeurologyNeuroscience
          ·June 6, 2019·4 min read

          Scientists recreate blood-brain barrier defect outside the body

          Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips.
          Read More
          This shows a brain with the chemical structure of cbd
          FeaturedNeuroscience
          ·April 17, 2019·2 min read

          Cannabidiol could help deliver medications to the brain

          Cannabidiol may be able to bypass the blood-brain barrier to effectively deliver medications directly to the brain.
          Read More
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          This shows a woman surrounded by red balls.

          Jamais Vu: When the Familiar Turns Eerily New

          This shows neurons.

          New Tools Illuminate Myelin Growth in Infants

          This shows a fly.

          From Vinyl to Visions: Fruit Flies Showcase Decision-Making Prowess

          This shows jellyfish.

          Jellyfish Show Remarkable Learning Skills

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