Researchers have pinpointed how brain activity changes in mouse models of Parkinson's disease, providing clues as to what may drive symptoms of the disease in humans.
Abnormal activity involving the globus pallidus may be responsible for movement dysfunction in Parkinson's disease, a new study reports.
Neurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease.
Researchers have identified a comprehensive circuit mechanism that governs how emotional states can influence movement through connections in the basal ganglia. The mechanism represents a way in which emotional states relate to changes in action control in depression, anxiety, and OCD.
A new study reveals a lack of dopamine transmission via D1 receptors disrupts information flow in the basal ganglia and can cause difficulty in initiating voluntary movements for Parkinson's patients.
Researchers discover children with Tourette syndrome are faster at assembling sounds into words than typically developing children.
Researchers provide possible new insights into psychiatric disorders such as schizophrenia.
N-acetylcysteine appears to help enable dopamine neurons to recover some function, researchers report.
Neurons in the basal forebrain are responsible for our ability to swiftly halt a planned behavior, a new study reports.