The fetal gut has far better developed immune capabilities than previously thought. The findings could help develop new maternal vaccines and provide early insight into potential autoimmune disorders, which may occur later in life. Read More
Hematopoietic stem cell transplantation reversed neuromyelitis optica. Five years following transplantation, only 2 of twelve patients had relapsed. Read More
Oligodendrocyte progenitor cells (OPCs) actively contribute to neuroinflammation associated with multiple sclerosis. Read More
TH17 cells produced increased amounts of SerpinB1, a protein implicated in multiple sclerosis symptoms. SerpinB1 cells were identified with antibodies targeting the CXCR6 surface protein. Using monoclonal antibodies to target CXCR6, the cells disappeared significantly, and the mice primed to develop MS did not develop the disease. Read More
Embryonic damage caused by autoantibodies is implicated in a range of behavioral and psychological disorders, including schizophrenia, autism, and ADHD. Read More
Postural orthostatic tachycardia syndrome (POTS), a disorder characterized by sudden fainting, may be an autoimmune disease. A new study reveals 89% of patients with the condition had elevated levels of autoantibodies against the adrenergic alpha 1 receptor. The potential biomarker can be identified via blood samples. Read More
Ter119, an inflammatory antibody, has the potential to treat inflammation caused by autoimmune diseases, according to the findings of a new rodent study. Read More
Kdm6a, a gene on the X chromosome appears to be associated with the development of autoimmune diseases, such as Multiple Sclerosis. The gene is expressed more in the immune cells of females than males. When Kdm6a was deleted in mouse models of MS, the animals had improved symptoms and reduced inflammation. The findings shed light on why women are more prone to autoimmune diseases than males. Read More
Clotting proteins are elevated in the urine of patients with lupus nephritis. The findings provide a new biomarker for the autoimmune disease. Read More
A study of over 200,000 people found no evidence that vaccinations increase the risk of developing multiple sclerosis, or the onset of an initial MS episode. Read More
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy. Read More
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia. Read More
