Hematopoietic stem cell transplantation reversed neuromyelitis optica. Five years following transplantation, only 2 of twelve patients had relapsed.
Poor sleep and inadequate oxygen supply associated with obstructive sleep apnea appears to affect cytokines. This could explain the link between OSA and an increased risk of autoimmune disorders, such as rheumatoid arthritis.
Postural orthostatic tachycardia syndrome (POTS), a disorder characterized by sudden fainting, may be an autoimmune disease. A new study reveals 89% of patients with the condition had elevated levels of autoantibodies against the adrenergic alpha 1 receptor. The potential biomarker can be identified via blood samples.
Scars and lesions on the brain and spinal cord offer clues as to why progressive disability occurs in patients with multiple sclerosis.
18% of new patients treated at two Los Angeles hospitals for multiple sclerosis were misdiagnosed with the autoimmune disease. The misdiagnosed patients were often treated unnecessarily with medications designed for MS. From their findings, researchers report the most common alternative diagnosis was migraine.
A new study reveals a link between food allergies and relapses in Multiple Sclerosis.
A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.
A new study considers whether immune system changes in people with lupus contribute to neuropsychiatric symptoms associated with the disease.
Some of the T cell epitopes targeting myelin in monkeys were the same as those found in humans. Researchers say linking these specific cells opens the doors to developing antiviral therapies that could be useful to treat newly diagnosed cases of MS in humans.
Specific combinations of microorganisms in the gut can worsen symptoms of multiple sclerosis in mouse models of the autoimmune disease.