Neural progenitor cells generated from skin cell samples of people on the autism spectrum had heightened levels of DNA damage. The damage clustered in 36 of the same genes which had also been damaged in healthy cells exposed to replication stress. Twenty of the genes have previously been linked to the development of autism.
Successful social interactions for adults on the autism spectrum revolve around partner compatibility, not just the skill set of the other person.
Study identifies a short gene segment crucial for brain development and information processing. The absence of the gene segment induces altered social behaviors, learning difficulties, and memory deficits, which are hallmarks of a subset of ASD.
A drug commonly prescribed for edema improves the symptoms for young children on the autism spectrum with no significant side effects. The drug, bumetanide, decreases the ratio of GABA to glutamate in the brain.
In the largest genetic sequencing study of autism conducted to date, researchers have identified 102 genes associated with the neurodevelopmental disorder. 49 of the genes were also associated with other developmental delays. The new study has enabled the researchers to increase the number of ASD associated genes from 65 to 102.
Male patients on the autism spectrum who were given oxytocin for four weeks experienced improvements in social attachment behaviors for up to 12 months.
On average, girls on the autism spectrum are diagnosed 1.5 years later than boys. Over 50% of those on the autism spectrum exhibit co-occurring mental health and medical conditions, such as ADHD and epilepsy.
Musical anhedonia, a neurological condition where people don't enjoy music, affects 5% of the population. Researchers are exploring if this same condition could also be what impairs social bonding for some people on the autism spectrum.
Mothers on the autism spectrum are more likely to report symptoms of postnatal depression than mothers who do not have ASD.
p75NTR, a protein implicated in normal brain development and Alzheimer's disease, may play a role in the development of autism. Mice bred without the protein exhibited learning deficits similar to those associated with ASD.
A quarter of children under the age of eight on the autism spectrum are not being diagnosed, a new study reports. Those most affected are minority children.
Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.