Scientists have long believed that glioblastoma multiforme, the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. Researchers found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.
Astrocyte toxicity in ALS may be caused by an explicit loss on MHCI expression in motor neurons, a new study reveals.
Researchers report transplanting altered neural stem cells into the brains of mice genetically engineered to exhibit symptoms of ALS, delayed the progression of the disease and extended lifespan.
A new method for obtaining mature neuronal cells from reprogrammed skin cells allows researchers to safely and effectively study diseases such as schizophrenia and autism.
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Neuroscience researchers show how astrocytes control the generation of new neurons in the brain. “In the brain, astrocytes control how many new neurons are formed from neural stem cells and survive to integrate into the existing neuronal networks. Astrocytes do this by secreting specific molecules but also by much less understood direct cell-cell interactions with stem cells”, says Prof. Milos Pekny.