A new blood-brain barrier on a chip system is being used to study neuroinflammation, researchers report.
Researchers use a novel sequencing method to identify a group of genes used by microglia to sense pathogenic organisms, toxins and damaged neurons.
Findings could help develop new treatments for depression, researchers report.
New findings about how water enters neurons could help pave the way for the development of new therapies to treat edema.
Neuroscience researchers show how astrocytes control the generation of new neurons in the brain. “In the brain, astrocytes control how many new neurons are formed from neural stem cells and survive to integrate into the existing neuronal networks. Astrocytes do this by secreting specific molecules but also by much less understood direct cell-cell interactions with stem cells”, says Prof. Milos Pekny.
Axon regeneration and dramatic improvements in functional recovery occurred when lactate was applied to damaged neural tissue. Treatment with lactate also significantly improved locomotion and restored some walking capability in mouse models of SCI.
Astrocytes may lead the tempo of the body's internal clock and control patterns of daily behavior, a new study reports.
A new study reveals humans and mice have significant differences in how oxidative stress and inflammation trigger immune response genes in astrocytes. Researchers suggest lab models of neurodegeneration should incorporate specially engineered mouse models with lower resistance to oxidative stress, rendering them more human-like.
Following an induced stroke in mice, researchers find astrocytes help promote neurogenesis in the damaged part of the brain.
Researchers hope tracking the development of the spheroids and observing their interactions may shed light on human brain development and the molecular causes of neuropsychological disorders.
A new study sheds light onto the role astrocytes play in neurodevelopment.