The loss of the Arid1b gene interferes with brain cells implicated in signaling inhibition. Reduced inhibitory signaling has previously been associated with a range of autism-related behaviors.
Three different autism risk genes affect similar aspects of neural formation and the same types of neurons in the developing human brain.
Researchers report fetuses with a rare chromosomal aberration have a 20% increased risk of being diagnosed with a developmental disorder.
A GABA receptor modulating drug has been shown to reverse both social and cognitive deficits induced by a genetic mutation associated with autism and intellectual disabilities, researchers report.
Researchers investigate how the ARID1B gene may play a role in ASD, intellectual disabilities and Coffin-Siris syndrome.
A new study describes the genomic landscape of schwannoma brain cancers.
