When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.
A lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning.
A new study into human and plant cell apoptosis could provide new avenues for the development of treatments for neurodegenerative diseases, and help develop disease-resistant plants.
Chronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.
Gene therapy can restore the structure of the retina and regain normal light responses.
Vascular cell loss results in neuron loss, researchers report. However, pericytes secrete a substance that helps protect neurons, even when vascular cell degeneration begins to occur.
PET imaging of former NFL players who exhibited cognitive decline and psychiatric symptoms linked to CTE showed higher levels of tau in areas of the brain associated with the neurodegenerative disease.
Two different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria.
Night time white lighting in hospital rooms has been linked to higher rates of inflammation, apoptosis and mortality risk for those who have recently experienced a cardiac event.
Researchers may have solved one of the great mysteries of neuroscience; namely, why neurons in the temporal lobe are the first to die in Alzheimer's disease, and why dopaminergic neurons are damaged first in Parkinson's.
Researchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.
A new study reports the popular body building protein supplement, L-norvaline, can have a negative impact on brain health. Researchers found that in low concentrations, the supplement causes damage to neurons which eventually leads to cell death.
