A lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning.
Researchers have identified a mechanism triggered at neuron birth to intrinsically decrease apoptosis. When the genetic regulation is halted, continuous neuronal survival is disrupted, leading to a decrease in animal survival.
A new study reveals diet has an impact on the fitness of cells lining the intestinal tract. Researchers report in flies, dietary restrictions prevent leaky gut with aging, while a rich diet prompts intestinal permeability.
Researchers have identified a mechanism that integrates signals from the ongoing repair process and the cell death machinery.