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ApoE4

·December 6, 2017·5 min read

Alzheimer’s Damage Reduced with Compound that Targets APOE Gene: Mouse Study

Researchers from WUSTL have identified a compound that targets APOE in mouse brains and which protects against Alzheimer's disease. The APOE4 genetic variant increases the risk of people developing Alzheimer's disease. The findings offer new possible avenues of treating the disease in humans.

Image shows a jigsaw puzzle of a dna strand.

Featured Genetics Neurology Open Neuroscience Articles

·November 30, 2017·5 min read

Gene Variant That Protects Against Alzheimer’s Identified

Researchers report people with a genetic predisposition to Alzheimer's and who carry a variant in the RAB10 gene, may be more resilient to the disease than those without the genetic variant.

Featured Neurology

·November 2, 2017·4 min read

Middle Age Inflammation Linked to Brain Shrinkage Decades Later

According to a new study, people who have inflammation biomarkers in their blood during middle age are more likely to have increased brain shrinkage as they grow older. Researchers report the brain cell loss associated with inflammation was most prevalent in areas affected in Alzheimer's disease.

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·October 6, 2017·2 min read

Researchers Studying Drug’s Potential to Prevent Alzheimer’s

Researchers are testing whether low doses of Rapamycin, a drug most commonly used as an immunosuppressant following an organ transplant, can help to prevent Alzheimer's disease.

Featured Genetics Neurology

·September 22, 2017·4 min read

Multi-Gene Test Predicts Alzheimer’s Better Than ApoE4 Alone

UCSF researchers have developed a new genetic risk factor test that takes into account more than 24 genetic variants, each of which are associated with a small risk of Alzheimer's disease. The researchers say the test is a better method to help identify preclinical Alzheimer's than testing for ApoE4 alone.

Featured Neurology

·September 14, 2017·3 min read

Study Investigates Vaccine and Oral Medication to Stop Alzheimer’s Years Before it Begins

Researchers are testing a new vaccine and oral medication that could delay or prevent Alzheimer's disease from developing in those with a genetic predisposition.

Image shows a nurse drawing blood from an older man.

Featured Neurology Open Neuroscience Articles

·September 10, 2017·4 min read

Breakthrough Study Reveals New Diagnosis for Alzheimer’s

A new method of examining blood plasma allowed researchers to identify specific chemical bonds within the blood. The new technique allowed researchers to accurately distinguish between Alzheimer's disease and Lewy body dementia, thus reducing cases of misdiagnosis.

Featured Genetics Neurology Open Neuroscience Articles

·September 4, 2017·8 min read

Which Genetic Marker Is the Ring Leader in the Onset of Alzheimer’s Disease?

Researchers have implicated TOMM40, a gene adjacent to APOE on chromosome 19, in the development of Alzheimer's disease. TOMM40, researchers report, plays a significant role in the decline of verbal learning after the age of 60.

Featured Genetics Psychology

·July 23, 2017·4 min read

Gene Variant Increases Risk For Depression

According to researchers, people with the APOE4 gene have a 20% increased risk of developing depression as they age.

Image shows amyloid plaques in the brain.

Featured Neurology Open Neuroscience Articles

·June 15, 2017·5 min read

More Amyloid in the Brain, More Cognitive Decline

The amount of amyloid plaques present within a person's brain can indicate the rate at which their cognition will decline in the following four years, a new study reports.