According to researchers, humans have evolved unique gene variants that help protect aging adults from neurodegenerative diseases.
Boosting omega-3 fatty acid intake helps to preserve brain health and improve cognition in middle age, a new study reports. For those with the Alzheimer's associated APOE4 gene, omega-3 fatty acid intake was associated with greater hippocampal volume and less small vessel disease.
People with higher levels of omega-3 DHA in their blood are 49% less likely to develop dementia than those with lower levels. Researchers say adding additional omega-3 DHA to the diet, especially in those with the Alzheimer's associated Apoe4 gene, could slow the development and progress of dementia.
Dasatinib, an FDA-approved drug for chronic myeloid leukemia, and an experimental drug for liver cancer reduced neuroinflammation, tau phosphorylation, and amyloid secretion in cell cultures of post-mortem brain samples of those with the APOE4 Alzheimer's associated gene.
A gene variant responsible for vascular damage to the brain is a promising new target for drug therapy to fight...
ApoE2 appears to have neuroprotective properties and could be key in the fight against Alzheimer's disease, according to a new study.
Researchers report they have successfully erased damage caused by Apoe4 in Alzheimer's patients by altering the gene into a harmless Apoe3-like version.
Researchers are testing whether low doses of Rapamycin, a drug most commonly used as an immunosuppressant following an organ transplant, can help to prevent Alzheimer's disease.