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ApoE4

This shows an older lady sitting on a swing, smiling at her husband

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 1, 2021·4 min read

Healthy Lifestyle Linked to Better Cognition for Oldest Adults, Regardless of Genetic Risk

Adults over 80 who maintained a healthy lifestyle, including exercise and diet, had a lower risk of cognitive decline, even if they had genetic risk factors for dementia.

Featured Neurology Neuroscience Visual Neuroscience

·May 14, 2021·5 min read

The Eyes Offer a Window Into Alzheimer’s Disease

Retinal scans can help researchers detect Alzheimer's disease and track its progression in those with the APOE4 genetic risk factor for the neurodegenerative disorder. The scans can detect blood vessel deterioration linked to the genetic biomarker.

Featured Genetics Neurology Neuroscience

·May 6, 2021·3 min read

Discovery of Genetic Drivers Linked to Progression in Parkinson’s Disease

Researchers identify five genetic loci linked to the progression of Parkinson's disease.

This shows people walking and cycling in a park

Featured Neurology Neuroscience

·March 31, 2021·2 min read

Exercise May Help Slow Cognitive Decline in Some People With Parkinson’s Disease

Exercise helped to reduce cognitive decline two years later in Parkinson's patients with the APOE e4 gene variant.

Featured Genetics Neurology Neuroscience

·March 18, 2021·4 min read

Could Leak in Blood-Brain Barrier Be Cause of Poor Memory?

Researchers investigate the role the blood-brain barrier may play in age-related memory problems.

Featured Genetics Neurology Neuroscience

·March 3, 2021·5 min read

Why the APOE4 Gene Enhances Alzheimer’s Risk

APOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer's disease and slow cognitive decline.

This shows a doctor looking at a spinal cord x ray

Featured Neurology Neuroscience

·February 26, 2021·5 min read

The Impact of Patient Sex on Treatment Strategies for Spinal Cord Injuries

Both the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.

This shows an older man holding his head in pain

Featured Genetics Neurology Neuroscience Pain

·February 24, 2021·4 min read

Pain Perception Could Help Diagnose Alzheimer’s Before Symptoms Occur

Altered pain perception could be a new biomarker to assess late-onset Alzheimer's risk in cognitively healthy individuals with the AopE4 gene before symptoms occur.

Featured Genetics Neurology

·February 11, 2021·5 min read

Spinal Fluid of People With Alzheimer’s Risk Gene Signals Inflammation

People with the APOE4 genetic risk factor for Alzheimer's disease also have lower levels of the CRP inflammatory molecules in their spinal fluid. Researchers speculate these inflammatory molecules may be accumulating in the brain and causing damage, rather than floating freely in cerebrospinal fluid.

This shows a man in a facemask surrounded by representations of covid-19

Featured Genetics Neurology Neuroscience

·February 4, 2021·4 min read

The Link Between ‘Alzheimer’s Gene’ and COVID-19

ApoE4, a gene associated with an increased risk of Alzheimer's disease, also appears to increase susceptibility and the severity of COVID-19. SARS-CoV-2, the virus responsible for coronavirus, increased susceptibility to COVID-19 in ApoE4 neurons and astrocytes in brain organoid models.

Featured Genetics Neurology Open Neuroscience Articles

·October 6, 2020·6 min read

Alzheimer’s Risk Gene Disrupts Endocytosis, but Another Disease-Linked Gene Could Help

The Alzheimer's risk gene ApoE4 hampers the process of endocytosis in astrocytes.

This shows a head made up of network nodes

Featured Genetics Neurology Open Neuroscience Articles

·July 18, 2020·5 min read

Adults With Alzheimer’s Risk Factors Show Subtle Alterations in Brain Networks Despite Normal Cognition

APOEe4, a gene associated with Alzheimer's disease risk, doesn't appear to directly affect memory performance or brain activity in older adults without cognitive impairment. However, the gene does seem to influence brain regions and systems that older at-risk adults activate to support successful memory recall.

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ApoE4

Healthy Lifestyle Linked to Better Cognition for Oldest Adults, Regardless of Genetic Risk

The Eyes Offer a Window Into Alzheimer’s Disease

Discovery of Genetic Drivers Linked to Progression in Parkinson’s Disease

Exercise May Help Slow Cognitive Decline in Some People With Parkinson’s Disease

Could Leak in Blood-Brain Barrier Be Cause of Poor Memory?

Why the APOE4 Gene Enhances Alzheimer’s Risk

The Impact of Patient Sex on Treatment Strategies for Spinal Cord Injuries

Pain Perception Could Help Diagnose Alzheimer’s Before Symptoms Occur

Spinal Fluid of People With Alzheimer’s Risk Gene Signals Inflammation

The Link Between ‘Alzheimer’s Gene’ and COVID-19

Alzheimer’s Risk Gene Disrupts Endocytosis, but Another Disease-Linked Gene Could Help

Adults With Alzheimer’s Risk Factors Show Subtle Alterations in Brain Networks Despite Normal Cognition

From Vinyl to Visions: Fruit Flies Showcase Decision-Making Prowess

Jellyfish Show Remarkable Learning Skills

Upside Down World: Unique View Offers Clues to Face Recognition

Brain’s Blue Spot, Locus Coeruleus, Is A Key Player in Sleep Quality and Memory

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