Disulfiram, a drug commonly prescribed to treat chronic alcohol addiction, was shown to reduce anxiety levels in rodent models. The drug inhibits FROUNT protein and chemokine signaling pathways under its influence, suppressing overall glutamate transmission in the brain. This, in turn, helps reduce overall activity. The findings may signal a new way to treat anxiety in humans.
Researchers from EPFL have uncovered how diazepam, a common anxiolytic, can increase mitochondrial activity in neural pathways associated with motivation.
Study reveals a possible mechanism by which anxiolytic medications act on the brain, leading to cognitive impairment.
Scientist reveal a drug regiment consisting of anti-inflammatories and anti-stress medications given before and after surgery could reduce cancer recurrence.